MANDATORY NOTIFICATION OF TRADE BY PRIMARY INSIDERS AND CLOSE ASSOCIATES

Oslo, Norway (29 March 2021) - Reference is made to the offer document dated 8 March 2021 (the "Offer Document") for the recommended voluntary offer by Compagnie des Levures Lesaffre (the "Offeror") to acquire all outstanding shares in NattoPharma ASA ("NattoPharma" or the "Company") against a consideration in cash of NOK 35 per share (the "Offer"), and further reference is made to the stock exchange announcement dated 29 March 2021 in which the Offeror announced that the voluntary offer is completed. The Offeror had obtained pre-commitments from Shareholders representing approximately 65.10% (on a Fully Diluted basis, excluding treasury shares) of the Shares to tender their Shares pursuant to the Offer. The pre-commitments included 1,655,122 shares by primary insiders of the Company and 7,855,611 shares by close associates of primary insiders of the Company (as listed below): · Bohan & Co AS as close associate to Chairman of the Board sold 1,298,455 shares in this transaction. Following this transaction Bohan & Co AS will not hold any shares in NattoPharma. · TG Montgomery AS as close associate to Chairman of the Board Frode Bohan and deputy Board Member Kim Øien sold 2,121,482 shares in this transaction. Following this transaction TG Montgomery AS will not hold any shares in NattoPharma. · Patrycja Ratunsinska as close associatie to Chairman of the Board sold 350,000 shares in this transaction. Following this transaction Patrycja Ratunsinska will not hold any shares in NattoPharma. · Primary insider and Chairman of the Board Frode Bohan sold 100,000 shares in this transaction. Following this transaction Frode Bohan will not hold any shares in NattoPharma. · Nicole Invest AS as close associate to deputy Board Member Kim Øien sold 200,000 shares in this transaction. Following this transaction Nicoline Invest AS will not hold any shares in NattoPharma. · Grethe Eggesbøe Thorsheim as close associate to Board Member Sjur Thorsheim sold 21,000 in this transaction. Following this transaction Grethe Eggesbøe Thorsheim will not hold any shares in NattoPharma. · Pro AS as close associate to Board Member Sjur Thorsheim sold 2,861,310 shares in this transaction. Following this transaction Pro AS will not hold any shares in NattoPharma. · Primary insider and Board Member Sjur Thorsheim sold 100,000 shares in this transaction. Following this transaction Sjur Thorsheim will not hold any shares in NattoPharma. · Life Science Sweden AB as close associate to Board Member Stefan Hallden sold 647,654 shares in this transaction. Following this transaction Life Science Sweden AB will not hold any shares in NattoPharma. · Primary insider and Board Member Stefan Hallden sold 310,800 shares in this transaction. Following this transaction Stefan Hallden will not hold any shares in NattoPharma. · Tontine AB as close associate to Board Member Stefan Hallden sold 81,210 shares in this transaction. Following this transaction Tontine AB will not hold any shares in NattoPharma. · Primary insider and Board Member Annette Elmqvist sold 150,000 shares in this transaction. Following this transaction Annette Elmqvist will not hold any shares in NattoPharma. · Primary insider and Board Member Katarzyna Maresz sold 125,000 shares in this transaction. Following this transaction Katarzyna Maresz will not hold any shares in NattoPharma. · Cinco Invest AS as close associate to Chief Executive Officer Kjetil Ramsøy sold 300,000 shares in this transaction. Following this transaction Cinco Invest AS will not hold any shares in NattoPharma. · Primary insider and Chief Executive Officer Kjetil Ramsøy sold 275,100 shares in this transaction. Following this transaction Kjetil Ramsøy will not hold any shares in NattoPharma. · Primary insider and Chief Financial Officer Robert Schrama sold 33,000 shares in this transaction. Following this transaction Robert Schrama will not hold any shares in NattoPharma. · Primary insider Elise Kaiser sold 40,000 shares in this transaction. Following this transaction Elise Kaiser will not hold any shares in NattoPharma. · Primary insider Laura Bakker sold 81,000 shares in this transaction. Following this transaction Laura Bakker will not hold any shares in NattoPharma. · Primary insider Andrew Green sold 20,000 shares in this transaction. Following this transaction Andrew Green will not hold any shares in NattoPharma. · Primary insider Randall Eric Anderson sold 191,750 shares in this transaction. Following this transaction Randall Eric Anderson will not hold any shares in NattoPharma. · Primary insider Rudi De Man sold 86,000 shares in this transaction. Following this transaction Rudi De Man will not hold any shares in NattoPharma. · RDM Health & Nutrition BVBA as close associate to Primary Insider Rudi De Man sold 60,500 shares. Following this transaction RDM Health & Nutrition BVBA will not hold any shares in NattoPharma. · Primary insider William Sommer sold 142,472 shares in this transaction. Following this transaction William Sommer will not hold any shares in NattoPharma. Please refer to the attached notifications of trading for further details. *** For more information, please contact: Robert Schrama, CFO E-mail: robert.schrama@nattopharma.com This information is subject to the disclosure requirements pursuant to section 5 -12 of the Norwegian Securities